17 December 2024
The Garrod Award recognises exceptional contributions from non-clinical scientists to the field of rheumatology. The spotlight shines on Dr Matteo Vecellio, a Versus Arthritis Career Development Fellow at the University of Oxford’s Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences (NDORMS).
Dr Vecellio’s story is one of dedication, collaboration, and breakthrough research, making his journey a testament to the significance of applying for the Garrod Award.
A moment of pride
Reflecting on his win, Dr Vecellio says,
“It’s an honour to receive the Garrod Award. It’s one of the most recognised prizes in the UK for rheumatology, and I knew the competition was tough. This award isn’t just about me—it’s a celebration of my team’s collective efforts.”
From Milan to Oxford: A journey in research
After earning his PhD in Translational and Molecular Medicine at the University of Milan in 2012, Dr Vecellio honed his skills at Goethe University in Frankfurt before joining NDORMS in 2013. Collaborating with Professor Paul Wordsworth, he began exploring the genetic underpinnings of ankylosing spondylitis (AS).
Breakthrough research
Dr Vecellio’s research focuses on the genetic association between ankylosing spondylitis (AS) and the RUNX3 gene, employing innovative techniques to uncover pathways crucial to gene regulation. His work has led to:
- The first publication on the functional genetic association of RUNX3 with AS.
- Ongoing research with potential applications to other genetic associations in rheumatology.
- Insights that may pave the way for new treatments for AS and related conditions.
“Our work has identified potential pathogenic pathways that are crucial for gene regulation. These findings could not only aid in developing targeted therapies for AS but also have implications for other polygenic rheumatic diseases.”
The value of encouragement
Dr Vecellio was inspired to apply for the Garrod Award by a colleague and previous winner, Dr Liye Chen:
“He encouraged me to apply, believing I met the criteria. I also had the incredible support of Professor Wordsworth, whose mentorship has been pivotal in my journey.”
This highlights the importance of mentorship and peer encouragement in advancing a research career.
Award impact and looking ahead
Winning the Garrod Award has brought renewed focus and validation to Dr Vecellio’s work,
“This recognition validates that we are on the right path. It’s a boost for our team and could open doors for collaboration and funding opportunities.”
Looking to the future, Dr Vecellio aims to continue uncovering RUNX3 mechanisms through a novel combination of immunology and functional genomics. He aims to secure new grants to expand his team and further the impact of his research.
Why you should apply
The Garrod Award is more than a prize—it’s a platform to propel your research, amplify your impact, and gain recognition among peers and collaborators. Dr Vecellio’s story illustrates how applying for such an award can validate years of challenging work and inspire the next generation of breakthroughs.
If you’re considering applying, take the leap. As Dr Vecellio’s journey shows, the award not only recognises individual excellence but also celebrates the collective achievements of research teams striving to improve lives through science.